Repeated oxytocin prevents central sensitization by regulating synaptic plasticity via oxytocin receptor in a chronic migraine mouse model

Abstract Background Central sensitization is one of the characters of chronic migraine (CM).Aberrant synaptic plasticity can induce central sensitization.Oxytocin (OT), which is a hypothalamic hormone, plays an important antinociceptive role.However, the antinociceptive effect of OT and the underlying mechanism in CM remains unclear.Therefore, we e

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Immersion freezing by natural dust based on a soccer ball model with the Community Atmospheric Model version 5: climate effects

We introduce a simplified version of the soccer ball model (SBM) developed by Niedermeier et al (2014 Geophys.Res.Lett.http://dx.doi.org/10.1002/2013GL058684 41 http://dx.doi.org/10.1002/2013GL058684 ) into the Community Atmospheric Model version 5 (CAM5).It is the first time that SBM is used in an atmospheric model to parameterize the heterogeneou

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